Table 2.
Outcome | Explanatory variable | Test | Statistic | df | p-Value |
---|---|---|---|---|---|
Overall survival (OS) | geno50 | Log-Rank | 1.72 | 2 | 0.42 |
geno50.bis | Log-Rank | 1.54 | 1 | 0.22 | |
geno20 | Log-Rank | 1.21 | 1 | 0.27 | |
Relapse/progression | geno50 | χ2 | 2.32 | 2 | 0.31 |
geno50.bis | Fisher | – | – | 0.68 (two-sided) | |
geno20 | Fisher | – | – | >0.99 (two-sided) | |
aGVHD | geno50 | χ2 | 0.69 | 4 | 0.95 |
geno50.bis | χ2 | 0.5 | 2 | 0.78 | |
geno20 | χ2 | 0.63 | 2 | 0.73 | |
cGVHD | geno50 | χ2 | 1.38 | 2 | 0.5 |
geno50.bis | Fisher | – | – | 0.83 (two-sided) | |
geno20 | Fisher | – | – | 0.27 (two-sided) | |
Survival status at this date | geno50 | χ2 | 7.55 | 4 | 0.11 |
geno50.bis | χ2 | 6.59 | 2 | 0.04 | |
geno20 | χ2 | 1.08 | 2 | 0.58 | |
Overall survival (OS) | DPB1 matching | Log-Rank | 0.52 | 2 | 0.77 |
aGVHD | DPB1 matching | χ2 | 7.64 | 2 | 0.02 |
Relapse/progression | DPB1 matching | χ2 | 7.01 | 2 | 0.03 |
Geno50: recipients carrying 2, 1 or 0 common haplotypes with a frequency ≤ rank 50; geno50.bis: recipients carrying 2 common haplotypes with a frequency ≤ rank 50 versus recipients carrying any rare haplotypes with a frequency > rank 50; geno20: recipients carrying 0 or 1 rare haplotype versus recipients carrying 2 rare haplotypes with a frequency > rank 20
aGVHD acute graft vesus host disease, cGVHD chronic graft versus host disease, df degrees of freedom