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. 2019 Apr 5;54(10):1701–1709. doi: 10.1038/s41409-019-0520-6

Table 2.

Clinical outcome following HSCT: summary of univariate analyses

Outcome Explanatory variable Test Statistic df p-Value
Overall survival (OS) geno50 Log-Rank 1.72 2 0.42
geno50.bis Log-Rank 1.54 1 0.22
geno20 Log-Rank 1.21 1 0.27
Relapse/progression geno50 χ2 2.32 2 0.31
geno50.bis Fisher 0.68 (two-sided)
geno20 Fisher >0.99 (two-sided)
aGVHD geno50 χ2 0.69 4 0.95
geno50.bis χ2 0.5 2 0.78
geno20 χ2 0.63 2 0.73
cGVHD geno50 χ2 1.38 2 0.5
geno50.bis Fisher 0.83 (two-sided)
geno20 Fisher 0.27 (two-sided)
Survival status at this date geno50 χ2 7.55 4 0.11
geno50.bis χ2 6.59 2 0.04
geno20 χ2 1.08 2 0.58
Overall survival (OS) DPB1 matching Log-Rank 0.52 2 0.77
aGVHD DPB1 matching χ2 7.64 2 0.02
Relapse/progression DPB1 matching χ2 7.01 2 0.03

Geno50: recipients carrying 2, 1 or 0 common haplotypes with a frequency ≤ rank 50; geno50.bis: recipients carrying 2 common haplotypes with a frequency ≤ rank 50 versus recipients carrying any rare haplotypes with a frequency > rank 50; geno20: recipients carrying 0 or 1 rare haplotype versus recipients carrying 2 rare haplotypes with a frequency > rank 20

aGVHD acute graft vesus host disease, cGVHD chronic graft versus host disease, df degrees of freedom