Table 3.
Cox regression model for overall survival with geno50
| 95.0% CI for Exp(B) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Explanatory variable | B | SE | Wald | df | Sig. | Exp(B) | Lower | Upper |
| TX center | 22.715 | 3 | 0 | |||||
| 2 | −0.592 | 0.344 | 2.965 | 1 | 0.085 | 0.553 | 0.282 | 1.085 |
| 3 | 1.017 | 0.31 | 10.754 | 1 | 0.001 | 2.765 | 1.506 | 5.078 |
| 4 | 0.789 | 0.69 | 1.309 | 1 | 0.253 | 2.201 | 0.57 | 8.509 |
| Age | 10.77 | 3 | 0.013 | |||||
| Age (20–40) | 1.02 | 0.543 | 3.528 | 1 | 0.06 | 2.773 | 0.957 | 8.041 |
| Age (40–60) | 1.03 | 0.473 | 4.735 | 1 | 0.03 | 2.801 | 1.108 | 7.081 |
| Age (>60) | 1.688 | 0.528 | 10.206 | 1 | 0.001 | 5.409 | 1.92 | 15.236 |
| Disease stage | 11.286 | 2 | 0.004 | |||||
| Disease stage (intermediate) | 0.268 | 0.285 | 0.888 | 1 | 0.346 | 1.308 | 0.748 | 2.285 |
| Disease stage (advanced) | 1.042 | 0.317 | 10.828 | 1 | 0.001 | 2.835 | 1.524 | 5.272 |
| DPB1 MM | 0.628 | 2 | 0.731 | |||||
| DPB1 MM (1 MM) | 0.084 | 0.319 | 0.07 | 1 | 0.791 | 1.088 | 0.583 | 2.032 |
| DPB1 MM (2 MM) | −0.145 | 0.353 | 0.169 | 1 | 0.681 | 0.865 | 0.433 | 1.729 |
| geno50 | 0.805 | 2 | 0.669 | |||||
| geno50 (1 common haplotype) | 0.291 | 0.377 | 0.595 | 1 | 0.44 | 1.337 | 0.639 | 2.799 |
| geno50 (0 common haplotype) | 0.376 | 0.428 | 0.771 | 1 | 0.38 | 1.456 | 0.63 | 3.368 |
Baseline for TX center = 1, for age = <20, for disease stage = early, for DPB1 MM = 0 MM, for geno50 = 2 common haplotypes. MM mismatch, TX transplant