Table 2.

A list of variants that were reclassified to actionable.

Gene	Variant	Neutral result returned to participant?	Time between neutral report and reclassification (days)
MSH2a	Deletion exons 4–6	Yes	529
MSH2a	Deletion exons 1–3	Yes	603
BRCA1a	Deletion exons 13–15	No	38
CHEK2	Deletion exons 1–15	Yes	603
BRCA2b	Deletion exons 1–27	Yes	605
RB1b	Deletion exons 1–27
F5	Homozygous c.1601G>A	Yes	321

^aParticipant had result documented in the EHR before study related return of results.

^bTwo reclassified variants in a single participant.