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. 2020 May 4;11(5):312. doi: 10.1038/s41419-020-2499-8

Fig. 6. TPL inhibited tumor growth and proliferation of tumor cell in xenograft animal model.

Fig. 6

a, b Time course and survival curves of SKOV3 tumor growth in control (blue, 0.9% NaCl 0.4 ml/25 mg, i.p., daily) and TPL-treated (red, TPL 1.6 mmol/kg, i.p, once a day,7 days/week) mice (n = 6–9 per group). c The H&E staining of kidneys and liver from mouse in both treatments (scale bars, 100 μm). d Representative images of Ki-67 staining of tumor tissues (scale bars, 50 μm) from mouse in both treatments, and association analyses of the number of Ki-67 + cells in tumor tissues. e The representative image of fluorescent DAPI and TUNEL staining of xenograft tumor sections, and association analysis of number TUNEL positive cells (scale bars, 50 μm). Data are the mean ± SD for experiments. *P < 0.05; **P < 0.01; ***P < 0.001; no sign means no significant difference; Student’s t-test.