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. 2020 May 4;11:2189. doi: 10.1038/s41467-020-15768-x

Fig. 6. COSMIC mutational signatures.

Fig. 6

COSMIC SNV mutation signatures identified in TGCT, organized by histology and platinum response. Analyses were performed on 247 primary tumours with exome sequencing data (ICR1, ICR2, DFCI and TCGA series) after excluding nine primary tumours with missing histology. Signatures were derived from somatic SNVs from primary tumours pooled together within each group as indicated. COSMIC signatures 1, 3 and 19 are displayed separately, whilst other represents the contribution from the remaining signatures combined.