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. 2020 May 4;10:7435. doi: 10.1038/s41598-020-64277-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Increases in glial fibrillary acidic protein (GFAP) positive cells in the isocortex (CTX) of SCR-KO mice. (a) The HPF, CTX, and thalamus (TH) were stained with primary antibodies against GFAP (scale bar, 100 μm). (b) Number of GFAP-positive cells per unit tissue area (mm²) was counted and compared in each brain region between WT (n = 7 mice) and SCR-KO mice (n = 7 mice) (* p < 0.05).