Table 2.

List of direct targets of selected miRNAs highly expressed in CESCs and their functional role.

miRNA	Targets	Functional role	Reference
Hsa-miR-143-3p	MAPK7	Inhibits adipocyte proliferation and enhance their differentiation	58
		Inhibits proliferation, cell migration and invasion of breast cancer	59
	KRAS	Suppresses colorectal cancer cell growth	60
	IGF1R	Regulates cell proliferation and apoptosis	61
		Regulation of myogenesis	62
	PIK3R1	Down regulation promotes propagation, migration, epithelial mesenchymal transition and stem cell phenotype of renal canal cells	63
Hsa-miR-21-5p	MEF2C	Crucial for neuronal function	64
Hsa-miR-10a-5p	PTEN	Tumor suppressor	65
Hsa-miR-150-5p	VEGFA	Decrease migration, invasion and angiogenesis in Rheumatoid arthritis	66
	CREB1	A novel Wnt effector that may enhance epithelial mesenchymal transition of colorectal cancer cells	67
	CDK2	Inhibits proliferation and tumorigenicity via retarding G1/S phase transition	68
	TP53	Promotes proliferation of lung cancer cells	69,70