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A Alignment of Rev amino acid sequences of different HIV-1 clades. Key domains of Rev are also marked by lines. Substitutions or deletions within each region are shown; conserved amino acids are indicated with point (.), deletions are shown with dash (-) and the star (*) represents the premature stop codon. Clade D have the same deletions (QSQGVET) as clade B. B Frequency of premature stop codon within Rev of different HIV-1 clades.
