Table 3.
Clinical Characteristics of Affected Eye
| Left Eye (N = 6) | Right Eye (N = 10) | |
|---|---|---|
| Affected Eye, n (%)a | 6 (100.0%) | 10 (100.0%) |
| Lesion Location, n (%) | ||
| Central | 5 (83.3%) | 9 (90.0%) |
| Peripheral | 1 (16.7%) | 1 (10.0%) |
| Underlying Cause of NK, n (%) | ||
| Herpes keratitis | 0 (0.0%) | 1 (10.0%) |
| Herpes zoster keratitis | 2 (33.3%) | 2 (20.0%) |
| Corneal surgery | 0 (0.0%) | 1 (10.0%) |
| Dry eyes | 0 (0.0%) | 1 (10.0%) |
| Diabetes | 0 (0.0%) | 1 (10.0%) |
| Neurosurgical procedure | 1 (16.7%) | 0 (0.0%) |
| Otherb, c | 3 (50.0%) | 4 (40.0%) |
| Snellen Score, n (%) | ||
| 20/20 | 1 (16.7%) | 0 (0.0%) |
| 20/150 | 1 (10.0%) | 0 (0.0%) |
| 20/1333 | 1 (10.0%) | 0 (0.0%) |
| 20/2666 | 2 (20.0%) | 0 (0.0%) |
| 20/8000 | 2 (20.0%) | 2 (33.3%) |
| Light Perception | 1 (10.0%) | 1 (16.7%) |
aNot mutually exclusive. Two participants had NK in both eyes
bOther underlying causes of NK in the right eye include: “partial limbal stem-cell deficiency” (n = 1), “herpes simplex keratitis” (n = 1), “Fuchs dystrophy” (n = 1), and “neurotrophic kertoconjunctivitis” (n = 1)
cOther underlying causes of NK in the left eye include: “partial limbal stem-cell deficiency” (n = 1), “herpes simplex keratitis” (n = 1), and “Stevens-Johnson syndrome” (n = 1)
Abbreviations: NK Neurotrophic keratopathy