TABLE 3.
Analyses (t-test) for the seed-voxel functional connectivity analysis for typical readers and children with reading difficulties; contrast: Left amygdala vs. right amygdala (p < 0.05, FDR corrected).
| Group | Amygdala seed (contrast) | Clusters (anatomical regions) | Number of voxels in the cluster | X | Y | Z | Effect size (beta) | T |
| TR | R > L | Right temporal pole | 5027 | 24 | 0 | −16 | 0.15 | 14.9 |
| TR | L > R | Left insular cortex | 2671 | −24 | 0 | −16 | 0.16 | 15.6 |
| Left cingulate gyrus | 317 | −22 | −16 | 44 | 0.07 | 4.97 | ||
| RD | R > L | Right temporal pole | 2201 | 26 | 0 | −16 | 0.24 | 9.03 |
| Right middle frontal gyrus | 267 | 28 | 32 | 26 | 0.11 | 4.64 | ||
| RD | L > R | Left hippocampus | 2937 | −26 | 0 | −18 | 0.21 | 7.88 |
FDR, false discovery rate; TR, typical readers; RD, children with reading difficulties; L, left; R, right; X/Y/Z, centroid coordinates.