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. 2020 Apr 28;8:234. doi: 10.3389/fcell.2020.00234

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Copyright © 2020 Liu, Liu, Fang, Xue, Zou, Tseng and Konnikova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tree-structure visualization for SPADE and FlowSOM. (A) SPADE tree colored by CD3 intensity. (B) FlowSOM tree with multiple maker intensities. Both tools were applied to the example from Figure 2.