Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 28;10:557. doi: 10.3389/fonc.2020.00557

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Jun, Peng, Zhang and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) IC₅₀ concentrations of JEG3 and its chemoresistant sublines treated with MTX, 5-Fu, or VP16, respectively. n = 3, *P < 0.05, JEG3 sublines vs. JEG3. (B) Experimental scheme for the quantitative proteomic analysis on JEG3 and its chemoresistant sublines. (C) The number of differentially expressed proteins identified by TMT labeling and LC-MS/MS in JEG3 and its chemoresistant sublines. Criteria were set for up-regulation (JEG3 sublines vs. JEG3, fold change ≥ 1.5) and down-regulation (JEG3 sublines vs. JEG3, fold change ≤ 0.67). (D) Top enriched molecular pathways/biological processes of up-regulated or down-regulated proteins in JEG3/MTX. (E) Top enriched molecular pathways/biological processes of up-regulated or down-regulated proteins in JEG3/5-Fu. (F) Top enriched molecular pathways/biological processes of up-regulated or down-regulated proteins in JEG3/VP16.