Table 3.
Multivariable cox regression analysis predicting mortality risk for metastatic GC both in unmatched and matched cohorts.
| Unmatched cohort | Matched cohort | |||||
|---|---|---|---|---|---|---|
| Characteristics | n | HR (95CI%) | p-Value | n | HR (95CI%) | p-Value | 
| Age at diagnosis (years) | ||||||
| 20–39 | 26 | 1[Reference] | NA | 20 | 1[Reference] | NA | 
| 40–59 | 107 | 1.28 (0.73–2.24) | 0.39 | 64 | 1.16 (0.64–2.12) | 0.62 | 
| 60–79 | 109 | 1.27 (0.71–2.28) | 0.42 | 74 | 1.10 (0.60–2.02) | 0.75 | 
| >=80 | 7 | 0.92 (0.29–2.95) | 0.89 | 4 | 0.52 (0.12–2.30) | 0.39 | 
| Sex | ||||||
| Male | 174 | 1[Reference] | NA | 115 | 1[Reference] | NA | 
| Female | 75 | 0.85 (0.58–1.24) | 0.39 | 47 | 0.85 (0.56–1.29) | 0.45 | 
| Race | ||||||
| White | 179 | 1[Reference] | NA | 123 | 1[Reference] | NA | 
| Black | 27 | 1.05 (0.59–1.86) | 0.86 | 11 | 0.74 (0.34–1.59) | 0.44 | 
| Others | 43 | 0.85 (0.53–1.37) | 0.51 | 28 | 0.89 (0.54–1.49) | 0.67 | 
| T stage | ||||||
| T1 | 21 | 1[Reference] | NA | 17 | 1[Reference] | NA | 
| T2 | 15 | 1.74 (0.72–4.25) | 0.22 | 8 | 0.97 (0.34–2.75) | 0.95 | 
| T3 | 88 | 1.07 (0.56–2.04) | 0.84 | 65 | 0.59 (0.31–1.13) | 0.11 | 
| T4 | 80 | 1.13 (0.56–2.33) | 0.71 | 45 | 0.77 (0.40–1.49) | 0.43 | 
| TX | 45 | 0.90 (0.47–1.72) | 0.76 | 27 | 1.17 (0.57–2.40) | 0.67 | 
| N Stage | ||||||
| N0 | 50 | 1[Reference] | NA | 34 | 1[Reference] | NA | 
| N1 | 89 | 1.22 (0.76–1.95) | 0.41 | 68 | 1.21 (0.73–2.03) | 0.46 | 
| N2 | 49 | 1.22 (0.69–2.17) | 0.49 | 31 | 0.81 (0.43–1.54) | 0.53 | 
| N3 | 49 | 1.74 (1.00–3.04) | 0.05 | 18 | 1.55 (0.77–3.1) | 0.22 | 
| NX | 12 | 1.24 (0.61–2.55) | 0.55 | 11 | 1.73 (0.81–3.68) | 0.16 | 
| Location | ||||||
| Cardia & Fund | 132 | 1[Reference] | NA | 98 | 1[Reference] | NA | 
| Body | 21 | 0.85 (0.44–1.65) | 0.63 | 17 | 0.68 (0.36–1.26) | 0.22 | 
| Antrum & Pylorus | 39 | 1.82 (1.00–3.30) | 0.05 | 21 | 0.87 (0.49–1.56) | 0.64 | 
| Others | 57 | 2.10 (1.20–3.68) | 0.01 | 26 | 1.14 (0.68–1.91) | 0.62 | 
| Surgery | ||||||
| No | 103 | 1[Reference] | NA | 81 | 1[Reference] | NA | 
| Yes | 146 | 0.23 (0.14–0.36) | <0.0001 | 81 | 0.31 (0.21–0.46) | <0.0001 |