Table 1.
Diffusion tensor imaging-based studies of spontaneous subarachnoid hemorrhage-related brain injury.
| Authors | Number of patients | Duration to initial DTI | Pathology & lesion location | Analyzed neural structure | DTT methods | Limitations |
|---|---|---|---|---|---|---|
| Hong et al. (3) | 11 | 54.1 days (29-97) |
ACoA (11 patient) |
Cingulum, Fornix |
Configuration DTT parameters (FA↓, MD↑, TV↓) |
No detailed neuropsychological tests, Small number of subjects |
| Schweizer et al. (4) | 1 | 303 days | Not described | Hippocampus, dorsolateral Prefrontal lesion |
Configuration DTT parameters (FA↓) |
No control data, case study |
| Yeo et al. (5) | 22 | 7.3 ± 3.1 weeks | Not described | Corticospinal tract | DTT parameters (FA↓: midbrain) MD(-) |
No analysis of other motor tracts |
| Jang et al. (6) | 16 | 5.7 ± 1.5 weeks | Not described | Mammillothalamic tract | DTT parameters (FA↓,TV↓) |
No detailed neuropsychological tests |
| Jang et al. (7) | 17 | 6.2 weeks (3-10) |
ACoA:14pts PCoA:1pt ACA:1pt ICA:1pt |
Corticoreticular pathway | DTT parameters (FA↓, MD↑) FV↓ |
No detailed analysis of other motor tracts |
| Jang and Kim (8) | 24 | 6.49 weeks (3.14–13.86) |
ACoA:14pts PCoA:3pts MCA:2pts Other:5pts |
Lower ARAS | DTT parameters (FA:-, MD:-) TV↓ |
No analysis of other ARAS |
| Jang and Yeo (9) | 1 | 3 months | ACoA | Papez circuit | Configuration DTT parameters (FA↓, MD↑, FV↓) |
Case study |
| Jang and Seo (10) | 1 | 4 weeks | PCoA | Optic radiation | (FA-,ADC-, FN↓) | Case study |
| Jang et al. (11) | 21 | 5.9 weeks (3-12) |
ACoA:15pts ACA:3pts PCoA:1pt other |
Optic radiation | DTT parameters (FA↓, ADC↑,FN:-) |
No visual field test |
| Darwazeh et al. (12) | 21 | 8.92 ± 2.4 weeks | Not described | Mammillothalamic tract | DTT parameters (FA↓, ADC↑) |
No detailed neuropsychological tests |
| Jang and Yeo (13) | 1 | 9 weeks | MCA bifurcation | Precommissural Fornix | Configuration DTT parameters (FA↓, MD↑, FV↓) |
Case study |
| Reijmer et al. (14) | 49:SAH 22:unruptured aneurysm |
2 weeks 6 months |
Not described | White matter | DTT parameters (FA-, MD↓) |
Non-specific DTI analysis |
DTI, diffusion tensor imaging; DTT, diffusion tensor tractography; ACoA, anterior communicating artery; FA, fractional anisotropy; MD, mean diffusivity; TV, tract volume; PCoA, posterior communicating artery; ACA, anterior cerebral artery; ICA, Internal carotid artery; FV, fiber volume; MCA, middle cerebral artery; ARAS, ascending reticular activating system; ADC, apparent diffusion coefficient; FN, fiber number; SAH, subarachnoid hemorrhage.