Skip to main content
. 2020 Apr 28;11:260. doi: 10.3389/fendo.2020.00260

Figure 2.

Figure 2

Effects of CCBs with a final concentration of 10 μM on aldosterone secretion and proliferation in APA cells. (A) Effects on aldosterone secretion (mean ± SE, N = 15); B and C. Effect on aldosterone secretion in different genotypes (mean ± SE) (B) KCNJ5G151R, N = 7; (C) KCNJ5L168R, N = 5; (D) Effects on CYP11B2 mRNA expression (mean ± SD, N = 9); (E) Effects on cell proliferation (mean ± SD, N = 3). Cont, control; Beni, benidipine; Mibe, mibefradil; Nife, nifedipine; Aldosterone concentration or cell proliferation in control group was set as 100%; *P < 0.05; **P < 0.01; ***P < 0.001.