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. 2020 Apr 28;11:260. doi: 10.3389/fendo.2020.00260

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Copyright © 2020 Wang, Ma, Tong, Zhang, Wen and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Effects of ACTH, ATII and potassium on aldosterone secretion (A, mean ± SE, N = 7) and cell proliferation (B, mean ± SD, N = 6). (C) Effects of nifedipine on basal or ACTH-, ATII- and potassium-induced aldosterone secretion (mean ± SE, N = 4). (D) Effects of nifedipine on basal and ACTH-, ATII- and potassium-induced cell proliferation (mean ± SD, N = 4). Control, ACTH, ATII and potassium group were only compared with its corresponding group treated with nifedipine in (C,D); Cont, control; K, potassium, a final concentration of 15 μM; ATII, angiotensin II, a final concentration of 100 nM; ACTH: a final concentration of 100 nM *P < 0.05; ***P < 0.001.