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. 2020 Apr 28;7:190. doi: 10.3389/fvets.2020.00190

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Copyright © 2020 Cui, Xu, Zhou, Xu, Wang, Xiao, Li and Bi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemical detection of FAdV antigens in the liver, spleen, kidney, heart, and thymus tissues after infection with FAdV CH/HBTF/1710 isolate at 5 to 7 dpi. Positive signals for FAdV antigen were extensively detected by immunohistochemical staining in the liver (A,F,K), spleen (B,G,L), kidney (C,H,M), heart (D,I,N), and thymus (E,J,O) in the two infection groups and the contact sentinels at 5-7 dpi. No FAdV antigen was detected in the liver (P), spleen (Q), kidney (R), heart (S), and thymus (I) in the control group. Solid arrows indicate positive signals for viral antigen. Scale bar = 50 μm.