Figure 7.

Glycolysis and adenosine signaling in Sf-21 cells regulate the permissiveness of baculovirus infection. Sf-21 cells were preincubated with 2DG and Dipy (A) and adenosine (Ado) (B) before BmNPV or AcMNPV infection, respectively. The virus titers were estimated at 48 h postinfection. “Cell only” indicates cells without virus and drug treatments. All values are shown as the mean ± SEM of three replicates. Significance was determined by one-way ANOVA with Tukey's HSD post-hoc analysis; different letters for the treatment groups indicate significant differences at P < 0.05.