Figure 1.

PF ameliorates H₂O₂-induced cytotoxicity in melanocytes. (A) Melanocytes were treated with different concentrations of PF for indicated times. Cell proliferation was determined by MTS assay. Melanocytes were pretreated with PF for 24 h (B) or 48h (C) and then exposed to 1.0 mM H₂O₂ for another 24 h. The cell viability was determined by MTS. All data were presented as the mean ± standard deviation across three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ns, not significant. H₂O₂, hydrogen peroxide; PF, Paeoniflorin; h, hours; M, mol/L.