Table 1.
Baseline Characteristics of Subjects Enrolled in the Genetic Epidemiology of COPD Study
| Parameter | Value |
|---|---|
| No. of subjects enrolled | 10,198 |
| Age, y | 59.5 ± 9.0 |
| Female sex | 4,746 (46.5) |
| African-American race | 3,412 (33.5) |
| BMI, kg/m2 | 28.8 ± 6.3 |
| Current smoker | 5,416 (53.1) |
| Oxygen supplementation | 1,174 (11.5) |
| Lung function | |
| FEV1, L | 2.24 ± 0.9 |
| FEV1, % predicted | 76.3 ± 26 |
| FVC, L | 3.30 ± 1.0 |
| FVC, % predicted | 86.9 ± 18 |
| FEV1/FVC | 0.67 ± 0.2 |
| GOLD severity, % | |
| Stage 0 | 4,387 (43.0) |
| Stage I | 788 (7.7) |
| Stage II | 1,925 (18.9) |
| Stage III | 1,164 (11.4) |
| Stage IV | 606 (5.9) |
| PRISm | 1,323 (12.4) |
| SGRQ score | 27.4 ± 23 |
| 6-Min walk distance, feet | 1,350 ± 399 |
| mMRC score (IQR) | 1.37 (3) |
| % Emphysema (–950 Hu), total lung | 6.3 ± 9.8 |
| % Gas trapping (–856 Hu), total lung | 21.4 ± 19.7 |
Data are presented as mean ± SD or No. (%) unless otherwise indicated. Hu = Hounsfield units; IQR = interquartile range; mMRC = Modified Medical Research Council; PRISm = preserved ratio impaired spirometry; SGRQ = St. George’s Respiratory Questionnaire.