Table 2.

PASE scores and Functional Connectivity after controlling for markers of cardiovascular health (Model 1; N = 179) and cerebrovascular health (Model 2; N = 175).

	Intra subcortical				Inter executive-subcortical
	Beta Coefficient	Lower 95% CI	Upper 95% CI	P > |z|	Beta Coefficient	Lower 95% CI	Upper 95% CI	P > |z|
Model 1
Age	0.003	−0.020	0.025	0.797	−0.008	−0.031	0.080	0.374
Education	0.047	−0.018	0.111	0.158	0.060	−0.006	0.125	0.073
Sex	0.027	−0.259	0.313	0.852	−0.086	−0.375	0.203	0.559
Blood	0.002	−0.005	0.009	0.0560	0.002	−0.005	0.009	0.595
pressure	−0.014	−0.025	−0.002	0.017	−0.007	−0.019	0.004	0.220
Heart rate	0.021	−0.011	0.053	0.205	−0.005	−0.037	0.027	0.764
BMI
Within-subject PASE	0.329	0.090	0.569	0.007	0.266	0.023	0.509	0.032
Between-subject PASE	−0.042	−0.187	0.103	0.573	−0.066	−0.212	0.080	0.374
Model 2
Age	−0.002	−0.026	0.022	0.872	−0.010	−0.035	0.015	0.434
Education	0.042	−0.023	0.107	0.201	0.059	−0.007	0.124	0.081
Sex	0.014	−0.299	0.327	0.929	−0.112	−0.431	0.207	0.493
Blood	0.0001	−0.007	0.007	0.971	0.0002	−0.007	0.008	0.960
pressure	−0.013	−0.025	−0.001	0.032	−0.007	−0.019	0.006	0.005
Heart rate	0.023	−0.009	0.056	0.162	−0.0001	−0.033	0.033	0.995
BMI
Network FA	−1.358	−5.378	2.661	0.508	−2.647	−6.581	1.286	0.187
Subcortical	0.00001	−0.00009	0.0001	0.824	−0.00009	−0.0002	0.00005	0.187
GMV	—	—	—	—	0.00002	−0.000001	0.00004	0.151
Exec GMV
Within-subject PASE	0.313	0.071	0.554	0.011	0.277	0.023	0.531	0.032
Between-subject PASE	−0.043	−0.190	0.103	0.562	−0.060	−0.208	0.088	0.428

Note. Network FA/MD/GMV reflects either striatal or frontal-striatal structures for the intra subcortical and inter executive-subcortical FC models, respectively. Abbreviations: BMI, body mass index; PASE, Physical Activity Scale for the Elderly; FA, fractional anisotropy; MD, mean diffusivity. The significance of bold values is p< 0.05.