Figure 5.

Intracortical Projections Are Sufficient to Mediate Membrane Potential Changes in Cortical Neurons

(A) Schematic (left) of the experimental configuration for slice recordings and representative traces from a ChR2-negative layer V pyramidal neuron (right) during stimulation of layer V.

(A₁) Zoom-in of the response shown in (A).

(B–B₂) Positive peak amplitude (B), negative peak amplitude (B₁), and area (B₂) of the light-evoked response in ChR2-negative layer V principal neurons. n = 12; paired t test.

(C–D₂) Same as in (A)–(B₂), respectively, for ChR2-negative layer II/III pyramidal neurons. n = 10; paired t test (D), Wilcoxon test (D₁), and paired t test (D₂).

(E–F₂) Same as in (A)–(B₂), respectively, for ChR2-negative layer IV principal neurons. n = 10; paired t test.

See also Tables S3 and S5.