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. 2020 Apr 20;8(4):e14306. doi: 10.2196/14306

Table 2.

Summary of activity, sleep, and circadian rhythm patterns used in this study.

Categorya and pattern Description
Activity

M10 Average activity for the 10 most active hours

M10 time Start time of 10 most active hours

L5 Average activity for the 5 least active hours

L5 time Start time of 5 least active hours

RA Relative amplitude of most and least active hours

MDA Mean diurnal activity (rise time to bed time)

MNA Mean nocturnal activity

MA Mean activity with diurnal and nocturnal components

Diurnal skewness Skewness of the probability distribution of diurnal activity

Percentiles diurnal activity 5, 25, 50, 75, 95 percentiles of diurnal activity

% nocturnal activity (% NA) Ratio of nocturnal activity over sum 24-hour activity

IS1 Interday stability using 1-hour windows

IS2 Interday stability using 1-hour windows with 30-min overlap

IV1 Intraday variability (24 hours)

IV2 Intraday variability (1440 min)

IV3 Intraday variability (24 hours with 30-min overlap)

Activity TKEO diurnal Computing the diurnal activity variability using the Teager-Kaiser Energy Operator (TKEO)

Activity ratio TKEO Ratio of diurnal activity variability against overall activity variability evaluated using TKEO

Activity RMSSD Computing the diurnal activity variability using the root mean squared successive differences (RMSSD)

Activity ratio RMSSD Ratio of diurnal activity variability against overall activity variability evaluated using RMSSD

CMSE Composite multiscale entropy, evaluating the complexity of the time series at 5, 30, 60, 120 min
Sleep

Sleep onset Time starting sleep

Sleep offset Wake up time

Sleep duration Duration of main (nocturnal) sleep

Number wake-up Number of wake-up periods during sleep

Wake after sleep onset (WASO) minutes Minutes awake interrupting sleep

Sleep entropy Entropy of the activity during sleep (variability of activity during sleep)

Percentiles sleep activity 5, 25, 50, 75, 95 percentiles of activity during sleep

Awakenings total minutes Total number of minutes awakenings lasted for each automatically detected nocturnal sleep
Circadian rhythm

Sleep temperature zenith Maximum temperature during sleep

Sleep temperature zenith time Time of maximum temperature during sleep

Sleep temperature nadir Minimum temperature during sleep

Sleep temperature nadir time Time of minimum temperature during sleep

Sleep temperature range Range of temperature during sleep

Sleep onset phase Successive differences in sleep onset timing

Sleep offset phase Successive differences in sleep offset timing

Cosinor: MESOR Cosinor model: average measure of rhythm

Cosinor: Amplitude Cosinor model: amplitude of fitted sinusoid

Cosinor: Phase Cosinor model: phase of fitted sinusoid

aFor algorithmic details, see Multimedia Appendix 1. Overall, we have 49 extracted patterns (counting the percentiles and the CMSE entries separately). We remark that the categorization of the patterns into the three groups (activity, sleep, and circadian rhythm) is for reporting convenience.