Table 3.

Multivariable Cox regression analysis with HRs for incident CTS and UNE in relation to diabetes mellitus

Variable	Model I*		Model II†
	HR (95% CI)*	P value	HR (95% CI)†	P value
CTS (n=1081)
Prevalent DM	2.52 (1.99 to 3.18)	<0.0001	2.10 (1.65 to 2.70)	<0.0001
Age	0.98 (0.97 to 0.99)	<0.0001	0.98 (0.97 to 0.99)	<0.0001
Sex	1.69 (1.47 to 1.95)	<0.0001	1.69 (1.45 to 1.96)	<0.0001
Body mass index	–	–	1.07 (1.06 to 1.08)	<0.0001
Hypertension	–	–	0.98 (0.85 to 1.12)	0.73
Current smoking	–	–	1.06 (0.92 to 1.23)	0.38
Alcohol consumption	–	–	0.99 (0.99 to 1.00)	0.18
Antihypertensive treatment	–	–	1.04 (0.88 to 1.24)	0.62
UNE (n=223)
Prevalent DM	2.51 (1.49 to 4.19)	<0.001	2.20 (1.30 to 3.74)	0.003
Age	0.95 (0.93 to 0.97)	<0.0001	0.96 (0.94 to 0.98)	<0.001
Sex	0.87 (0.66 to 1.16)	0.35	0.88 (0.65 to 1.19)	0.39
Body mass index	–	–	1.06 (1.02 to 1.09)	0.001
Hypertension	–	–	0.87 (0.64 to 1.19)	0.39
Current smoking	–	–	1.60 (1.21 to 2.15)	0.001
Alcohol consumption	–	–	0.99 (0.98 to 1.01)	0.68
Antihypertensive treatment	–	–	1.04 (0.70 to 1.54)	0.83

*Adjusted for sex and age at study entry.

†Adjusted for sex, age at study entry, alcohol consumption, body mass index (BMI), hypertension, the use of antihypertensive treatment, and smoking.

CTS, carpal tunnel syndrome; DM, diabetes mellitus; UNE, ulnar nerve entrapment.