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. 2016 Jul 15;311(3):H689–H698. doi: 10.1152/ajpheart.00264.2016

Fig. 2.

Fig. 2.

MiroRNA-140 is elevated in RV Su/Hx/Nx rats compared with RV normoxic rats. A: a subset of microRNA determined by unbiased microRNA microarrays that are differentially regulated more than 1 logFC between normal right ventricle (Nx RV) and hypertrophied RV at 8-wk Su/Hx/Nx PAH rats. B: qPCR validation of increase in miR-140 in the RV of the Su/Hx/Nx PAH rat. C: Pearson correlation between RVSP and miR-140 in the RV of 8-wk Su/Hx/Nx PAH rats. D: Pearson correlation between RV hypertrophy (Fulton's index) and miR-140 in the RV of 8-wk Su/Hx/Nx PAH rats. E: Pearson correlation between RVSP and miR-140 in the RV of 13-wk Su/Hx/Nx PAH rats. F: Pearson correlation between RV hypertrophy (Fulton's index) and miR-140 in the RV of 13-wk Su/Hx/Nx PAH rats. *P < 0.05 vs. normoxic control, #P < 0.05 vs. 8-wk Su/Hx/Nx. Data are means ± SE (n = 3–4).