5. Treatment‐related adverse events.
| Study | Intervention | Comparators | P value1 | ||||||
| Description | A/R | Type | Events | Description | A/R | Type | Events | ||
| Arnold 2001 | Salt bath + UVB | 16/20 | Burning erythema | 2 | Psoralen bath + UVA | 17/20 | Burning erythema | 2 | 1.0 |
| Brockow 2007a | Salt bath + UVB | 79/81 | Dermatitis solaris | 2 | UVB | 71/79 | Dermatitis solaris | 1 | 1.0 |
| Brockow 2007b | Salt bath + UVB | 76/81 | 3 x phototoxic reaction 1 × burning/stinging |
4 | UVB | 53/83 | 2x phototoxic reaction 3x dermatitis solaris |
5 | 0.4861 |
| Dawe 2005 | Salt bath + UVB | 41/60 arms or legs | 3 x itching, 2 x stinging 1 x itchy papular eruption |
6 | UVB | 41/60 arms or legs | n.a. | 0 | < 0.0257 |
| Gambichler 2001 | Salt bath + UVB | 10/10 elbows | n.a. | 0 | Tap water + UVB | 10/10 elbows | n.a. | 0 | 1.0 |
| Klein 2011 | Salt bath + UVB | 180/183 | 'Definite' or 'probable' events | 21 | UVB | 179/184 | 'Definite' or 'probable' events | 11 | 0.0943 |
| Leaute‐Labreze 2001 | Salt bath + UVB | 24/24 | Itching and burning in most cases | 12 | UVB | 21/21 | Itching and burning in most cases | 7 | 0.3661 |
| Schiener 2007 | Salt bath + UVB | 284/310 | Phototoxic reactions | 33 | UVB | 252/301 | Phototoxic reactions | 31 | 0.894 |
| Tap water + UVB | 266/301 | Phototoxic reactions | 19 | 0.0809 | |||||
| Psoralen bath + UVA | 297/321 | Phototoxic reactions | 16 | 0.0072 | |||||
| Grade IV or V erythemas | 3 | UVB | 252/301 | Grade IV or V erythemas | 1 | 0.6263 | |||
| Tap water + UVB | 266/301 | Grade IV or V erythemas | 2 | 1.0 | |||||
| Psoralen bath + UVA | 297/321 | Grade IV or V erythemas | 5 | 0.7252 | |||||
| Oedema2 | n.r. | n.r. | n.r. | Oedema2 | n.r. | n.a. | |||
| Blisters2 | n.r. | n.r. | n.r. | Blisters2 | n.r. | n.a. |
1: Estimated by review authors using Easy Fisher Exact Test Calculator (Social Science Statistics 2018); statistically signifiant P values (P < 0.05) in bold font.
2: Schiener 2007 reported seven patients who developed edema and four who developed blisters, but the adverse events were not linked to a treatment group.
A/R: number of analyzed/randomized people or limbs; n.a.: not applicable; n.r.: not reported; UVA: artivicial ultraviolet A light; UVB: artificial ultraviolet B light