Table 1.
Genes Associated with Peroxide Resistance
| FlyBase ID | Gene | Name | Lead Variant | Pmin | Pgene | FDR |
|---|---|---|---|---|---|---|
| FBgn0031803 | ppk14 | Pickpocket 14 | 2L_6353972_SNP | 2.12 × 10–6 | 9.00 × 10–6 | 0.004797 |
| FBgn0031261 | nAChRbeta3 | Nicotinic acetylcholine receptor beta 3 (Dbeta3) subunit | 2L_544231_SNP | 9.73 × 10–7 | 2.20 × 10–5 | 0.011704 |
| FBgn0031802 | ppk7 | Pickpocket 7 | 2L_6351358_SNP | 2.12 × 10–6 | 2.70 × 10–5 | 0.014337 |
| FBgn0034098 | krimp | FI20010p1 | 2R_12124705_SNP | 1.68 × 10–6 | 3.10 × 10–5 | 0.01643 |
| FBgn0034099 | CG15708 | AT21920p | 2R_12127442_SNP | 1.68 × 10–6 | 3.10 × 10–5 | 0.01643 |
| FBgn0005660 | Ets21C | DNA-binding protein D-ETS-6 | 2L_546065_SNP | 9.73 × 10–7 | 3.30 × 10–5 | 0.017424 |
| FBgn0002031 | l(2)37Cc | Protein l(2)37Cc | 2L_19121067_SNP | 7.57 × 10–6 | 4.50 × 10–5 | 0.023715 |
| FBgn0003963 | ush | Zinc finger protein ush | 2L_475238_SNP | 4.51 × 10–8 | 7.10 × 10–5 | 0.037346 |
| FBgn0031865 | Nha1 | Na[+]/H[+] hydrogen antiporter 1, isoform A | 2L_6860010_SNP | 5.32 × 10–8 | 0.000123 | 0.064575 |
| FBgn0020906 | Jon25Bi | Jonah 25Bi | 2L_4953449_SNP | 4.23 × 10–5 | 0.000214 | 0.112136 |
| FBgn0031655 | Marcal1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | 2L_4954910_SNP | 1.27 × 10–5 | 0.000253 | 0.132319 |
| FBgn0263831 | Gen | Flap endonuclease GEN | 3L_5141974_SNP | 7.43 × 10–6 | 0.000262 | 0.136764 |
| FBgn0037730 | DmelCG9444 | CG9444, isoform A | 3R_5506170_SNP | 9.71 × 10–5 | 0.000272 | 0.141712 |
| FBgn0005616 | msl-2 | E3 ubiquitin-protein ligase msl-2 | 2L_3461213_SNP | 3.65 × 10–5 | 0.000367 | 0.19084 |
| FBgn0263102 | psq | Pipsqueak, isoform M | 2R_6444567_SNP | 3.29 × 10–5 | 0.000373 | 0.193587 |
| FBgn0004103 | Pp1-87B | Serine/threonine-protein phosphatase alpha-2 isoform | 3R_8248858_SNP | 0.0001966 | 0.000437 | 0.226366 |
| FBgn0083960 | DmelCG34124 | FI23230p1 | 2L_4957415_SNP | 1.27 × 10–5 | 0.000461 | 0.238337 |
| FBgn0040510 | ACXA | Adenylyl cyclase X, isoform A | 2L_12920145_SNP | 5.17 × 10–5 | 0.000472 | 0.243552 |
| FBgn0085227 | CG34198 | HDC07368 | 2R_15569059_SNP | 0.0001068 | 0.000489 | 0.251835 |
| FBgn0040506 | ACXE | Adenylyl cyclase X, isoform E | 2L_12924675_SNP | 8.53 × 10–5 | 0.000517 | 0.265738 |
| FBgn0027109 | NPF | Neuropeptide F | 3R_12434359_SNP | 9.19 × 10–5 | 0.000578 | 0.296514 |
| FBgn0031538 | DmelCG3246 | CG3246 | 2L_3459329_SNP | 3.65 × 10–5 | 0.000611 | 0.312832 |
| FBgn0052391 | DmelCG32391 | Uncharacterized protein | 3L_7060319_SNP | 1.15 × 10–5 | 0.000723 | 0.369453 |
| FBgn0038043 | CG17202 | c-Myc-binding protein homolog | 3R_8247496_SNP | 0.0001966 | 0.000762 | 0.38862 |
| FBgn0005640 | Eip63E | Ecdysone-induced protein 63E, isoform N | 3L_3514849_SNP | 1.80 × 10–5 | 0.00091 | 0.46319 |
| FBgn0051641 | stai | stathmin | 2L_6099379_SNP | 6.01 × 10–6 | 0.000922 | 0.468376 |
| FBgn0014009 | Rab2 | GH01619p | 2R_2583312_SNP | 5.43 × 10–5 | 0.000932 | 0.472524 |
| FBgn0262467 | Scox | AT19154p | 2L_4967292_SNP | 0.0002591 | 0.000943 | 0.477158 |
| FBgn0040509 | ACXB | Adenylyl cyclase X, isoform B | 2L_12916421_SNP | 0.0003891 | 0.00096 | 0.4848 |
The gene identifications from Fly Base (FB) release 5.49 for all genes with Pgene FDR < 0.5. The variant with the smallest P value for each gene (Pmin) is listed as the lead variant