Fig. 2.

MiR-145-5p targeted SMAD4. a-b, Associations between the 3′UTRs of SMAD4 transcripts and miR-145-5p were assessed using dual luciferase test. c-d, Immunoblots and the quantitative evaluation of SMAD4 in SKOV-3 cells that were transfected for 24 h using miR-145-5p mimic (c) or miR-145-5p repressor (d). Data are presented as means ± SEM, n = 3. ^**P < 0.01, compared with the NC group