Table 3.
Univariate and multivariate logistic regression model about NC, HRT and OI protocols
| Crude OR (95% Cl) | P-value | Adjusted OR (95% Cl) | P-value | |
|---|---|---|---|---|
| HDP | ||||
| NC | 1 | 1 | ||
| HRT | 2.36 (1.86–2.99) | < 0.001* | 2.00 (1.54–2.60) | < 0.001* |
| OI | 1.34 (0.86–2.07) | 0.193 | 1.02 (0.62–1.65) | 0.853 |
| GDM | ||||
| NC | 1 | 1 | ||
| HRT | 1.25 (0.99–1.58) | 0.061 | 1.10 (0.84–1.45) | 0.470 |
| OI | 1.48 (1.04–2.10) | 0.028* | 1.49 (0.97–2.19) | 0.056 |
| Placenta previa | ||||
| NC | 1 | 1 | ||
| HRT | 1.48 (0.90–2.42) | 0.122 | 1.52 (0.88–2.64) | 0.133 |
| OI | 1.17 (0.50–2.75) | 0.720 | 1.35 (0.55–3.27) | 0.514 |
| Oligohydramnios | ||||
| NC | 1 | 1 | ||
| HRT | 0.80 (0.47–1.37) | 0.419 | 0.70 (0.40–1.24) | 0.225 |
| OI | 1.36 (0.67–2.75) | 0.399 | 1.06 (0.49–2.29) | 0.887 |
| PTB | ||||
| NC | 1 | 1 | ||
| HRT | 1.84 (1.47–2.30) | < 0.001* | 1.78 (1.39–2.28) | < 0.001* |
| OI | 1.76 (1.24–2.50) | 0.002* | 1.51 (1.02–2.23) | 0.041* |
| LBW | ||||
| NC | 1 | 1 | ||
| HRT | 1.67 (1.25–2.23) | 0.001* | 1.49 (1.09–2.06) | 0.014* |
| OI | 1.35 (0.83–2.20) | 0.231 | 1.17 (0.70–1.96) | 0.547 |
| SGA | ||||
| NC | 1 | 1 | ||
| HRT | 0.83 (0.60–1.15) | 0.271 | 0.85 (0.60–1.21) | 0.370 |
| OI | 1.46 (0.96–2.24) | 0.078 | 1.47 (0.94–2.31) | 0.092 |
| LGA | ||||
| NC | 1 | 1 | ||
| HRT | 1.16 (1.02–1.33) | 0.021* | 1.15 (0.99–1.33) | 0.058 |
| OI | 0.93 (0.75–1.16) | 0.505 | 0.98 (0.77–1.24) | 0.842 |
NC natural cycle, HRT hormone replacement therapy, OI ovulation induction, OR odds ratio, CI confidence interval, HDP hypertensive disorders of pregnancy, GDM gestational diabetes mellitus, PTB preterm birth, LBW low birth weight, SGA small for gestational age, LGA large for gestational age
Adjustment included age, body mass index, irregular menstruation, donor sperm using, FET cycle number, number of transferred embryos, vanishing twin gestation, preconceptional fasting glucose, systolic pressure, diastolic pressure, endometrial thickness, antral follicle count, testosterone level, anti-Müllerian hormone
*There were significant differences between groups