Table 2.
Respiratory symptoms, functional status, and exacerbations
| Vitamin D Deficient | Vitamin D Sufficient | p value (Univariate analysis) | Vitamin D Deficiency Effect Estimateb | p value (Multivariable regression) | |
|---|---|---|---|---|---|
| na | 534 | 957 | |||
| SGRQ total score | 33.23 (23.33) | 26.89 (21.19) | < 0.001 | 3.14 (1.12) | 0.005 |
| Chronic Bronchitis | 113 (21.2) | 204 (21.3) | 1.0 | 0.91 [0.68, 1.22] | 0.54 |
| BODE score | 1.68 (1.75) | 1.50 (1.72) | 0.068 | 0.061 (0.07) | 0.38 |
| MMRC dyspnea score | 1.67 (1.46) | 1.38 (1.42) | < 0.001 | 0.11 (0.074) | 0.16 |
| 6 min walk distance, feet | 1312.76 (366.38) | 1400.16 (361.25) | < 0.001 | −31.0 (18.9) | 0.1 |
| Exacerbations per year | 0.43 (0.76) | 0.43 (0.72) | 0.94 | 0.032 (0.041) | 0.44 |
| Severe exacerbations per year | 0.19 (0.52) | 0.14 (0.32) | 0.038 | 0.024 (0.023) | 0.3 |
Mean (SD) or N(%) are shown
aLongitudinal follow up cohort had 1491 subjects, due to missing data
bCovariates in linear and logistic regression include age, race, gender, current smoking status, smoking pack years, and FEV1 percent predicted. Beta (SE) or Odds Ratio (95% CI) are shown