Table 4.
Vitamin D Deficient | Vitamin D Sufficient | p value (Univariate analysis) | Vitamin D Deficiency Effect Estimate (SE)d | p value (Multivariable regression) | |
---|---|---|---|---|---|
nb | 549 | 970 | |||
% emphysema | 5.80 (8.33) | 7.33 (9.48) | 0.002 | 0.76 (0.49) | 0.12 |
15th percentile of lung density histogram (+ 1000 HU) | 85.70 (32.25) | 76.81 (28.45) | < 0.001 | −2.1 (1.42) | 0.14 |
% gas trapping | 21.47 (18.76) | 24.99 (19.20) | 0.002 | 1.81 (1.05) | 0.085 |
Segmental airway wall thickness | 1.08 (0.23) | 1.05 (0.22) | 0.019 | 0.027 (0.012) | 0.021 |
Pi10c | 2.44 (0.63) | 2.37 (0.59) | 0.053 | 0.058 (0.036) | 0.11 |
Segmental wall area % | 52.03 (8.65) | 51.07 (8.21) | 0.040 | 0.81 (0.48) | 0.092 |
Change in % emphysema | 0.88 (3.87) | 0.56 (4.21) | 0.17 | 0.36 (0.25) | 0.16 |
Change in % gas trapping | 3.44 (9.89) | 2.01 (9.09) | 0.024 | 0.73 (0.64) | 0.26 |
Change in segmental airway wall thickness | −0.00 (0.13) | 0.01 (0.11) | 0.12 | −0.0052 (0.0077) | 0.50 |
Mean (SD) or N(%) are shown
aEach row represents the outcome of a separate regression model
bCT scan data was available for 1519 subjects
csquare root of wall area of hypothetical airway with 10 mm internal perimeter
dCovariates in linear regression models include age, race, gender, BMI, current smoking status, and scanner model