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. 2020 May 4;2020(5):CD012955. doi: 10.1002/14651858.CD012955.pub2

Schilling 2018.

Study characteristics
Methods 4‐week trial with 2 arms
  1. Metacognitive training for borderline patients (B‐MACT)

  2. Active control intervention (PMR)


Duration of trial: 4 weeks
Duration of participation: 4 weeks
Country: Germany
Setting: not stated
Participants Method of recruitment of participants: recruited from the Deparment of Psychiatry of the Asklepios clinic, Germany
Sample size: 48
Diagnosis of borderline personality disorder: Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM‐IV)
Means of assessment: Structured Clinical Interview for DSM‐IV Axis II Disorders (SCID‐II)
Mean age: B‐MACT = 29.36 years (standard deviation = 10.46), PMR = 31.15 years (standard deviation = 9.59)
Sex: 91.7% female
Comorbidity: 31% = major depressive disorder, 23% = any anxiety disorder (including 12 patients with PTSD), 7% = alcohol or substance abuse, 9% = dependence
Inclusion criteria
  1. Diagnosis of borderline personality disorder

  2. Aged 18‐65 years old


Exclusion criteria
  1. History of severe neurological disorder

  2. Intelligent quotient less than 70

  3. Diagnosis of bipolar disorder

  4. Schizophrenia or dementia

  5. Alcohol or substance dependence with consumption in last 4 weeks

Interventions Experimental groupTreatment name: B‐MACT
Number randomised to group: 22
Duration: 4 weeks
Control/comparison groupComparison name: PMR
Number randomised to group: 26
Duration: 4 weeks
Both groupsConcomitant psychotherapy: not stated
Concomitant pharmacotherapy: yes; 56 of the 74 treated with psychotropic medication, not specified by group
Proportions of participants taking standing psychotropic medication during trial observation period: unclear
Outcomes Primary
  1. Borderline personality disorder severity, assessed by a translation of the clinician‐administered Zanarini Rating Scale for BPD (ZAN‐BPD)


Secondary
  1. Depression, assessed by the Beck Depression Inventory

  2. Attrition, in terms of patients lost after randomisation in each group

Notes Sample size calculation: no sample calculation
Ethics approval: yes
Comments from review authors:
  1. We received an additional article sent by email from Dr Schilling on 22 January 2019.

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: no information about randomisation method provided
Allocation concealment (selection bias) Unclear risk Comment: no information about allocation concealment provided
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Comment: no information about the blinding of assessors provided
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Comment: no data on attrition, no mention of ITT or imputation method
Selective reporting (reporting bias) Unclear risk Comment: no protocol found preventing us from making a clear assessment of reporting bias
Other bias High risk Treatment adherence
Comment: no data on treatment adherence
Allegiance bias
Comment: first author was principal investigator and delivered both interventions. She also developed the manual for B‐ MACT.
Attention bias
Comment: interventions were similar in length.