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EC50 values for three IRAK inhibitors conducted in WT and IRAK4 knockout BCBL-1 cell lines
| Cell line | EC50 value (μM)a
|
||
|---|---|---|---|
| IRAK inhibitor-1 | IRAK inhibitor-4 | IRAK inhibitor-1-4 | |
| BCBL-1 WT | 14.9 ± 15 | 5.5 ± 0.5 | 275 ± 52 |
| ΔIRAK4.1 | 21.9 + 38 | 6.7 + 1.7 | 334 ± 170 |
| ΔIRAK4.2 | 15.0 ± 16 | 5.1 ± 3.5 | 231 ± 236 |
Represented are the averages and standard deviations from 4 biological replicates.
