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CD8 reactivity against flavivirus MP in areas where flavivirus is endemic. Shown are percentages of CD3+ CD8+ IFN-γ-producing T cells after flavivirus MP stimulation for 6 h of PBMCs derived from blood bank donors in Nicaragua (n = 8) and Sri Lanka (n = 6). Statistical analyses were performed using paired nonparametric Wilcoxon test. **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. ns, not significant.
