TABLE 2.
Downregulated genes in EBNA3A mutant EBV-infected lymphomas that match previously reported EBNA3A targetsa
| Gene | RPKM in lymphomas infected with: |
Fold decrease | |
|---|---|---|---|
| WT | Δ3A | ||
| ITGAM | 1.19 | 0.27 | 4.35 |
| BIN1 | 2.68 | 1.27 | 2.11 |
| ZNF395 | 2.06 | 0.95 | 2.17 |
| TPCN1 | 1.63 | 0.86 | 1.89 |
| PFKFB4 | 0.86 | 0.30 | 2.89 |
| PLEKHA1 | 0.31 | 0.084 | 3.73 |
| IMPA2 | 0.92 | 0.13 | 7.22 |
| F13A1 | 4.32 | 1.03 | 4.20 |
| ID3 | 2.65 | 0.45 | 5.87 |
| CLEC2D | 31.43 | 11.48 | 2.74 |
| CHST12 | 7.74 | 3.83 | 2.02 |
| EPB41L2 | 4.60 | 1.31 | 3.51 |
| SLC16A7 | 5.73 | 2.57 | 2.23 |
| MSC | 15.80 | 4.37 | 3.62 |
| FCER1G | 12.70 | 0.38 | 33.76 |
| CLECL1 | 12.43 | 1.54 | 8.09 |
| PIK3R6 | 4.34 | 1.39 | 3.13 |
Genes downregulated in our RNA-seq results that are also decreased in previously published microarray data (19). Genes of interest are in boldface.