TABLE 2.
Polymorphisms in the BZLF1 gene and its promoter
| Cell linec | Mutation(s) in BZLF1 ORFa | Closest EBV strainb |
|---|---|---|
| sLCL-2 | C696G | E1563 Owv7 (IM) |
| sLCL-3 | B95-8 (IM) | |
| sLCL-4 | C188G | E1583 OWv7 (IM) |
| sLCL-5 | C696G | E1563 Owv7 (IM) |
| sLCL-6 | G616T C696G | GC-variant-9 |
| sLCL-7 | T383C G616T | GC-variant-9 |
| sLCL-8 | G616T | GC-variant-9 |
| sLCL-9 | B95-8 (IM) | |
| sLCL-10 | G616T | GC-variant-9 |
| sLCL-11 | A411C C696G | GK_BL67 |
| sLCL-12 | A471G | E1563 Owv7 (IM) |
| sLCL-14 | A301C | B95-8 (IM) |
| sLCL-15 | G616T | GC-variant-9 |
| IM-1 | C163T G616T | M-ABA |
| IM-2 | B95-8 (IM) | |
| IM-3 | C696G | E1563 Owv7 (IM) |
| IM-4 | B95-8 (IM) | |
| IM-6 | C169T G175A C181A T213C G403A T437C T459C A471G G613T | HL04 |
| IM-7 | C169T G175A C181A T213C G403A T437C T459C A471G G613T | HL04 |
| IM-8 | B95-8 (IM) | |
| IM-9 | C169T G175A C181A T213C G403A T437C T459C A471G G613T | HL04 |
| IM-10 | G610T | GC-variant-9 |
a
None of the cell lines showed mutations in the BZLF1 mini-Zp. ORF, open reading frame.
b
IM, infectious mononucleosis; GC, gastric cancer; HL, Hodgkin lymphoma.
c
All cell lines were EBV type A.