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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Virology. 2020 Mar 23;545:40–52. doi: 10.1016/j.virol.2020.03.005

Figure 6. Influenza severity is reduced in ATII cell-specific 155-KO mice.

Figure 6.

Effects of intranasal mock and IAV infection of wild-type (WT) C57BL/6 mice and C57BL/6-congenic, ATII cell-specific 155-KO (155-KOATII) mice for 6 days on: (a) Carotid arterial oxygen saturation (% SaO2); (b) Lung water content (wet:dry weight ratio); (c) Static lung compliance (CST; ml/cmH2O, x 10); and (d) Baseline total lung resistance (RBASAL; cmH2O.s/ml). n>10 per group. Broken horizontal lines indicate values in uninfected WT mice. All data were analyzed by ANOVA with a post hoc Tukey-Kramer multiple comparison post-test and are presented as mean ± SEM. #P<0.001, vs. WSN-infected WT mice.