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. 2020 Apr 28;11:742. doi: 10.3389/fmicb.2020.00742

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Copyright © 2020 Vogler, Karan, Renn, Vancea, Vielberg, Grötzinger, DasSarma, DasSarma, Eppinger, Groll and Rueping.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrostatic surface potential of CA_D. (A) CA_D Monomer and (B) CA_D Trimer electrostatic surface potential color-coded from red (negative potential) to blue (positive potential). (C) The surface potential of CA_D compared to mesophilic γ-CA homologs (Escherichia coli, 3tio; Salmonella enterica, 3r3r; Anaplasma phagocytophilum, 3ixc; Bacillus cereus, 1xhd; Brucella abortus, 4n27; Clostridium difficile, 4mfg). Unit: –5 to +5 k_bT/e (k_b as the Boltzmann constant, T as the temperature in Kelvin and e as the charge of an electron).