Table 4.
alcohol intake trajectory following a breast cancer diagnosis
| Predictors | Low maintainer1 (n=2,269) | Medium temporary decreaser(n=459) | High temporary decreaser(n=137) | ||
|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||
| Education (ref=high school or less) | |||||
| Some college | Ref | 1.50 (0.90, 2.49) | 0.12 | 0.62 (0.30, 1.31) | 0.21 |
| College and above | Ref | 1.93 (1.18, 3.16) | 0.01 | 0.74 (0.36, 1.49) | 0.40 |
| Income (ref=<$50K) | |||||
| $50K-$89K | Ref | 1.62 (1.20, 2.20) | <0.01 | 2.57 (1.50, 4.41) | <0.01 |
| $90K+ | Ref | 0.84 (0.49, 1.43) | 0.51 | 0.18 (0.02, 1.38) | 0.10 |
| Depressive symptoms (high vs. low) | Ref | 0.94 (0.66, 1.34) | 0.74 | 1.34 (0.76, 2.35) | 0.31 |
| Optimism (high vs. low) | Ref | 0.99 (0.74, 1.31) | 0.92 | 1.14 (0.70, 1.87) | 0.59 |
| Social support (high vs. low) | Ref | 1.27 (0.94, 1.73) | 0.13 | 1.07 (0.64, 1.80) | 0.80 |
| Worse PWB at 6 months (yes vs. no) | Ref | 0.89 (0.63, 1.27) | 0.53 | 1.03 (0.57, 1.85) | 0.93 |
| Worse CIPN at 6 months (yes vs. no) | Ref | 0.92 (0.68, 1.26) | 0.61 | 1.12 (0.67, 1.87) | 0.68 |
| Age at diagnosis (ref=age<50) | |||||
| 50–59 | Ref | 0.84 (0.51, 1.40) | 0.50 | 0.94 (0.37, 2.40) | 0.90 |
| 60–70 | Ref | 0.77 (0.41, 1.42) | 0.40 | 0.52 (0.18, 1.48) | 0.22 |
| 70+ | Ref | 0.90 (0.46, 1.73) | 0.74 | 0.40 (0.12, 1.28) | 0.12 |
| Race/ethnicity (ref=non-Hispanic White) | |||||
| non-Hispanic Black | Ref | 0.70 (0.37, 1.33) | 0.28 | NE | NE |
| non-Hispanic Asian | Ref | 0.17 (0.09, 0.31) | <0.01 | 0.09 (0.02, 0.39) | <0.01 |
| Hispanic | Ref | 0.45 (0.26, 0.78) | <0.01 | 0.14 (0.03, 0.59) | 0.01 |
| Other | Ref | 0.87 (0.39, 1.96) | 0.73 | 0.35 (0.05, 2.63) | 0.31 |
| Postmenopausal (yes vs. no) | Ref | 1.12 (0.68, 1.85) | 0.65 | 2.89 (1.24, 6.76) | 0.01 |
| Baseline BMI (ref=BMI <25 kg/m2) | |||||
| Overweight (BMI 25–29.9 kg/m2) | Ref | 0.91 (0.68, 1.22) | 0.53 | 1.20 (0.71, 2.04) | 0.49 |
| Obese (BMI 30+ kg/m2) | Ref | 0.40 (0.28, 0.58) | <0.01 | 0.66 (0.37, 1.19) | 0.17 |
| Stage (ref=Stage I) | |||||
| Stage II | Ref | 0.89 (0.64, 1.25) | 0.51 | 0.69 (0.38, 1.27) | 0.24 |
| Stage III | Ref | 0.96 (0.54, 1.71) | 0.90 | 1.08 (0.42, 2.78) | 0.87 |
| Stage IV | Ref | 1.30 (0.36, 4.74) | 0.69 | NE | NE |
| Number of lymph node removed (ref=0) | |||||
| 1 | Ref | 0.79 (0.36, 1.71) | 0.55 | NE | NE |
| 2+ | Ref | 0.83 (0.40, 1.73) | 0.62 | NE | NE |
| ER/PR status (Positive vs. negative) | Ref | 1.35 (0.76, 2.39) | 0.30 | 0.74 (0.25, 2.14) | 0.57 |
| Surgery (ref=lumpectomy) | |||||
| Mastectomy | Ref | 0.97 (0.71, 1.32) | 0.85 | 0.54 (0.32, 0.92) | 0.02 |
| None | Ref | 0.42 (0.04, 4.06) | 0.46 | NE | NE |
| Chemotherapy (ref=none) | |||||
| Neoadjuvant | Ref | 0.88 (0.38, 2.02) | 0.76 | 0.39 (0.05, 3.33) | 0.39 |
| Adjuvant | Ref | 0.83 (0.58, 1.20) | 0.33 | 0.71 (0.37, 1.34) | 0.29 |
| Hormonal therapy (yes vs. no) | Ref | 1.05 (0.67, 1.63) | 0.83 | 1.69 (0.68, 4.15) | 0.26 |
| Radiation (yes vs. no) | Ref | 1.29 (0.94, 1.76) | 0.12 | 0.74 (0.42, 1.28) | 0.28 |
Note
Abbreviations: OR, odds ratio; CI, confidence interval; BMI, body mass index; CIPN, chemotherapy -induced peripheral neuropathy; PWB, physical well-being; NE, not estimable.
1.
Trajectory groups were labeled by the relative level of baseline behavior (high, medium, or low), direction of change (increased, unchanged, or decreased), and the persistence of change (temporary or stable).