Table 2.
The docking scores of compounds 1–4 and gefitinib on EGFR and the double-strand model DNA.
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1 | 2 | 3 | 4 | L1 | L2 | Gefitinib |
|---|---|---|---|---|---|---|---|
| EGFR ATP binding pocket | 8.02 | 8.61 | 8.07 | 8.82 | 6.43 | 6.62 | 6.80 (Zhang et al., 2015) |
| DNA minor groove | 7.06 | 7.33 | 7.48 | 6.57 | – | – | 4.05 |
| DNA intercalation | 5.55 | 5.70 | 5.65 | 5.36 | – | – | – |
