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. Author manuscript; available in PMC: 2021 Feb 11.
Published in final edited form as: Hum Hered. 2020 Feb 11;84(3):127–143. doi: 10.1159/000504171

Table 5:

Constraints on one allele frequency given an LD value and allele frequency at the other locus, for the five measures. Here, we assume pA,pB12. Owing to symmetry in the loci, for |D|,r2,andr2/rmax2, fixing pA is equivalent to fixing pB.

Fixed allele frequency
pA pB
|D′| 0 ⩽ pB ⩽ 1 0 ⩽ pA ⩽ 1
r2 r2pA1+r2pApApBmin(12,pAr2r2pA+pA) r2pB1+r2pBpBpAmin(12,pBr2r2pB+pB)
|d| max(0,pA+|d|1|d|)pBpA pBpAmin(12,1|d|+|d|pB)
ρ 0 ⩽ pB ⩽ 1 0 ⩽ pA ⩽ 1
r2/rmax2 0 ⩽ pB ⩽ 1 0 ⩽ pA ⩽ 1