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Clinical characteristics of index cases + sibs and parents with ALS and ALS/FTD.
| Parents | Index cases + sibs | p | |
| Gender: M/F (ratio) | 14/30 (0.47) | 63/45 (1.4) | 0.004 |
| Age of onseta | 63.0 ± 9.7 (27) | 56.9 ± 9.3 (99) | 0.003 |
| Bulbar onset (%) | 43.5 | 35.5 | |
| Upper limb onset (%) | 8.7 | 20 | ns |
| Lower limb onset (%) | 43.5 | 42.5 | |
| Dementia (%) | 4.3 | 2 | |
| Age at deatha | 64.7 ± 10.7 (24) | 60.5 ± 8.9 (89) | 0.007 |
| ALS durationa | 39.6 ± 24.3 (26) | 37.2 ± 23.5 (87) | 0.710 |
M/F, male/female. aValue are means ± SD (n).
