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. 2020 Jan 8;2020:1980368. doi: 10.1155/2020/1980368

Table 2.

Prognostic factors for DFS and OS by univariate analysis.

Variables n DFS OS
3 yrs 5 yrs P 3 yrs 5 yrs P
Gender
 Male 166 30.7% 27.1% 49.4% 40.4%
 Female 22 40.9% 40.9% 0.195 59.1% 54.5% 0.112

Age (years)
 ≤50 100 32.0% 27.0% 48.0% 39.0%
 >50 88 34.1% 30.7% 0.282 53.4% 45.5% 0.334

HCC family history
 Yes 18 27.8% 16.7% 55.6% 55.6%
 No 170 32.9% 30.0% 0.451 50.0% 40.6% 0.226

HBsAg
 Negative 28 46.4% 46.4% 67.9% 53.6%
 Positive 160 29.4% 25.6% 0.030 47.5% 40.0% 0.073

AFP (ng/ml)
 <200 83 43.4% 42.2% 62.7% 54.2%
 ≥200 105 22.9% 18.1% <0.001 41.0% 32.4% 0.003

Edmondson grading
 I-II 142 37.3% 34.5% 55.6% 48.6%
 III-IV 46 15.2% 10.9% <0.001 34.8% 21.7% 0.001

Tumour size (cm)
 ≤5 69 53.6% 47.8% 73.9% 65.2%
 >5 119 19.3% 17.6% <0.001 37.0% 28.6% <0.001

Liver cirrhosis
 Absent 39 30.8% 25.6% 59.0% 46.2%
 Present 149 32.2% 29.5% 0.771 48.3% 40.9% 0.186

Capsulation
 Capsulated 130 40.0% 37.7% 60.8% 51.5%
 Noncaspulated 58 13.3% 8.6% <0.001 27.6% 20.7% <0.001

Tumour number
 Single 136 40.4% 36.0% 61.0% 52.9%
 Multiple 52 9.6% 9.6% <0.001 23.1% 13.5% <0.001

Vascular invasion
 Yes 33 3.0% 3.0% 15.2% 6.1%
 No 155 38.1% 34.2% <0.001 58.1% 49.7% <0.001

GSN
 Low expression 93 48.4% 46.2% 61.3% 57.0%
 High expression 95 15.8% 11.6% <0.001 40.0% 27.4% <0.001

DFS, disease-free survival; OS, overall survival; other abbreviations are as in Table 1.