Table 3.
Neuropsychological and ToM results within the aMCI group at each step of evaluation (T0: baseline; T1: 6-month evaluation; T2: 12-month follow-up).
| Evaluation (time interval) | |||||
|---|---|---|---|---|---|
| T0 mean ± SD | T1 mean ± SD | T2 mean ± SD | Time comparison p value (∗) |
Pairwise comparisons p value (#) |
|
| aMCI NC (N = 27) | |||||
| MoCA test | |||||
| TOT | 21.61 ± 2.11 | 22.86 ± 3.12 | 22.97 ± 3.50 | 0.012 | T0 < T1; T1 = T2; T0 < T2 |
| VSP | 2.98 ± 1.04 | 3.26 ± 1.05 | 3.30 ± 1.18 | 0.318 | T0 = T1 = T2 |
| EF | 2.41 ± 1.16 | 2.82 ± 1.03 | 3.27 ± 0.89 | <0.001 | T0 < T1; T1 < T2; T0 < T2 |
| M | 0.57 ± 1.23 | 1.21 ± 1.55 | 1.04 ± 1.51 | 0.049 | T0 < T1; T1 = T2; T0 = T2 |
| ATT | 5.67 ± 0.84 | 5.61 ± 0.86 | 5.77 ± 0.93 | 0.608 | T0 = T1 = T2 |
| L | 4.85 ± 1.03 | 4.74 ± 1.19 | 4.84 ± 0.93 | 0.876 | T0 = T1 = T2 |
| OR | 5.64 ± 0.65 | 5.57 ± 0.88 | 5.21 ± 1.35 | 0.035 | T0 = T1; T1 > T2; T0 > T2 |
|
| |||||
| ToM tasks | |||||
| SS task | 4.11 ± 1.93 | — | 5.33 ± 1.80 | 0.009 | T0 < T2 |
| RME test | 18.29 ± 6.39 | — | 18.63 ± 5.29 | 0.735 | T0 = T2 |
|
| |||||
| aMCI C (N = 1) | |||||
| MoCA test | |||||
| TOT | 18.53 | 11.53 | 7.53 | ||
| ToM tasks | |||||
| SS task | 6 | — | 0 | ||
| RME test | 18 | — | 13 | ||
∗Repeated Measure ANOVA (in bold the statistical significant values, p < 0.05); #pairwise comparisons with LSD post hoc correction (in bold the statistical significant values, p corrected < 0.05); aMCI = amnestic Mild Cognitive Impairment; N = number of subjects included in the analyses; SD = Standard Deviation; MoCA = Montreal Cognitive Assessment test; TOT = MoCA total score; VSP = visuospatial abilities; EF = executive functions; M = memory; ATT = attention; L = language; OR = orientation; ToM = Theory of Mind; DB = Deceptive Box task; SS = Strange Stories task; RME = Reading the Mind in the Eyes test.