Table 1.
Baseline characteristics of study population.
| Control (n = 48) | CAD (n = 248) | P value | |
|---|---|---|---|
| Age (years) | 61.15 ± 8.02 | 61.54 ± 8.36 | 0.705 |
| Sex (n, male) | 23 (47.9%) | 105 (42.3%) | 0.475 |
| Hypertension (n, %) | 0 (0%) | 126 (73.3%) | NS |
| Diabetes mellitus (n, %) | 0 (0%) | 53 (30.8%) | NS |
| Smoking (n, %) | 0 (0%) | 89 (51.7%) | NS |
| HbA1c (%) | 5.97 ± 0.68 | 6.35 ± 1.21 | 0.009∗∗ |
| CK-MB (U/L) | 9.2 (7.7, 11.4) | 11.0 (9.0, 13.4) | 0.003∗∗ |
| TnI | 0.003 (0.001, 0.008) | 0.007 (0.003, 0.023) | <0.001∗∗ |
| TC | 4.73 (3.98, 5.38) | 4.69 (4.09, 5.48) | 0.860 |
| TG | 1.21 (1.00, 1.67) | 1.51 (1.16, 2.04) | 0.011∗ |
| HDL-c | 1.35 (1.13, 1.60) | 1.17 (1.02, 1.35) | 0.002∗∗ |
| LDL-c (mg/dL) | 3.05 ± 0.63 | 2.88 ± 0.68 | 0.086 |
| Cr (mg/dL) | 70.06 ± 5.75 | 71.95 ± 9.27 | 0.066 |
| LVEF (%) | 60.33 ± 3.61 | 59.14 ± 5.42 | 0.145 |
| Gensini score | NS | 38 (17, 74) | NS |
| PCI (n, %) | NS | 100 (40.3%) | NS |
| VEGF (pg/mL) | 160.93 (121.09, 303.26) | 645.57 (319.48, 901.14) | <0.001∗∗ |
Date are expressed as mean ± SD (standard deviation), median (interquartile range), and absolute number (percentage). P value for comparison between the CAD and the control group. ∗∗P < 0.01. HbA1c: hemoglobin A1c; CK-MB: creatine kinase-MB; TnI: troponin I; TC: total cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; Cr = creatinine; LVEF: left ventricular ejection fraction; PCI: percutaneous coronary intervention; VEGF = vascular endothelial growth factor.