Table 3.
Familial aggregation of psychopathologic measures: SCL t score
Symptomatic dimensions | Control Mean ± SD | Unaffected first-degree relative Mean ± SD | Schizophrenia probands Mean ± SD | P-value | P-value adjusted for age |
---|---|---|---|---|---|
Obsessive–Compulsive | 40.5 ± 7.2 | 43.6 ± 8.2* | 51.0 ± 13.3*,† | <0.001 | 0.000 |
Interpersonal–Sensitivity | 43.1 ± 7.3 | 44.9 ± 8.5* | 53.3 ± 14.4*,† | <0.001 | 0.000 |
Depression | 40.6 ± 6.0 | 45.1 ± 9.0* | 51.4 ± 13.1*,† | <0.001 | 0.000 |
Hostility | 42.2 ± 4.9 | 45.0 ± 7.3* | 49.1 ± 11.8*,† | <0.001 | 0.000 |
Phobia | 43.3 ± 5.3 | 46.4 ± 23.7* | 55.9 ± 15.9*,† | <0.001 | 0.000 |
P < 0.05 vs controls by Scheffe test.
P < 0.05 vs first-degree relatives by Scheffe test.
SCL, symptom check list; t score, in psychometrics, a t score is a type of standard score computed by multiplying a z-score by 10 and adding 50.