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. Author manuscript; available in PMC: 2020 May 5.
Published in final edited form as: Pediatr Res. 2019 Nov 29;87(6):1060–1065. doi: 10.1038/s41390-019-0699-7

Table 1.

Estimated heritability (h2) of telomere length.

Age and sex adjusted Covariates adjusted
h2 (95% CI) p value h2 (95% CI) p value
Grandparents-parents-newborn family (na = 41) 0.64 (0.47–0.81) 0.001
Paternal grandfather-father-newborn trio (n = 41) 0.80 (0.37–1.23) 0.001
Maternal grandmother-mother-newborn trio (n = 41) 0.85 (0.52–1.18) 0.001
Grandparents-parent trio (n = 82) 0.56 (0.38–0.74) 0.001 0.55 (0.38–0.72)b <0.001
Grandfather-parent pair (n = 82) 0.58 (0.36–0.80) 0.004 0.56 (0.36–0.76)c <0.001
Grandmother-parent pair (n = 82) 0.69 (0.52–0.86) 0.001 0.60 (0.42–0.78)d 0.004
Parents-newborn trio (n = 41) 0.68 (0.53–0.84) <0.001 — —
Father-newborn pair (n = 41) 0.76 (0.60–0.92) 0.001 — —
Mother-newborn pair (n = 41) 0.89 (0.75–1.03) <0.001 — —
a

Number of pairs, trios, or families

b

Age, sex, grip strength, and dietary fat intake were included as covariates in the analytic model

c

Age, sex, body mass index, grip strength, mental component summary score of SF-36, dietary fat intake, current smoking, and hypertension were included as covariates in the analytic model

d

Age, grip strength, and mental component summary score of SF-36 were included as covariates in the analytic model