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. 2019 Jun 25;53(2):96–102. doi: 10.14744/SEMB.2019.00868

Table 1.

Safe age limits for antidiabetic drugs application in the elderly

Age and the treatment of antidiabetics
Metformin Not recommended for use after 80 years of age
Sulphonylureas, glinides No age restrictions
Pioglitazones Up to 75 years old
Sitagliptin, saxagliptin Safe for 65–75 years
Vildagliptin Safe for 75–84 years
GLP-1 A Up to 75 years old
SGLT2 inhibitors Up to 75 years old