Table 1.

Metastatic osteosarcoma patient characteristics and 223-radium alpha radiotherapy cycles

Patient	Age (years)	Relapses	Time to 223-radium	223-Radium infusions (#)	Alkaline phosphatase
					Pre	Post	% Change
A	36	2	20	3	97	65	−33%
B	15	2	39	6	112	80	−29%
C	26	1	25	2	1714	715	−62%
D	24	2	21	3	85	59	−31%
E	23	4	16	6	70	48	−325%
F	15	4	33	1	310	nd	---
G	11	2	13	5	1370	67	−95%
H	16	3	18	2	380	232	−39%
I	20	3	15	2	133	nd	--
J	24	2	52	2	131	125	−5%
K	18	1	18	6	94	50	−47%
L	14	1 (TNTC-LM)	16	4	198	70	−655%
M	11	0 (TNTC-B)	3	5	269	168	−38%
N	25	1 (TNTC-B)	18	1	653	220	−66%
O	19	2	20	2	403	1041	1.58
Median	19	2	20	3	198	80	−60%
Mean	20	2	21.9	3	401	226	−44%

Time to radium: months from diagnosis to 223-Ra infusion 1.

TNTC-B, too numerous to count—bone metastases; TNTC-LM, too numerous to count—lung metastases.