Table 4.
Association of morphological CAC features with CVD events
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Adjustment: Number of calcified segments |
||||||
| HR | 95%CI | p | HR | 95%CI | p | |
| Shape | ||||||
| Cylindrical | 1.71 | 1.25–2.33 | 0.001 | 1.15 | 0.81–1.62 | 0.424 |
| Spherical | 0.62 | 0.34–1.12 | 0.115 | 0.55 | 0.31–0.98 | 0.042 |
| Semi-tubular | 1.49 | 1.31–1.68 | <0.001 | 1.19 | 0.99–1.44 | 0.067 |
| Spotty | 1.30 | 1.15–1.47 | <0.001 | 0.89 | 0.74–1.06 | 0.182 |
| Location | ||||||
| Bifurcations | 1.31 | 1.11–1.55 | 0.001 | 0.87 | 0.67–1.09 | 0.233 |
| Myocardial side | 0.95 | 0.69–1.32 | 0.774 | 0.82 | 0.60–1.12 | 0.217 |
| Pericardial side | 0.71 | 0.47–1.07 | 0.103 | 0.66 | 0.45–0.98 | 0.039 |
| Both-sided | 1.40 | 1.24–1.57 | <0.001 | 1.07 | 0.90–1.28 | 0.456 |
| Regularity of boundaries | ||||||
| Regular | 1.13 | 0.93–1.37 | 0.209 | 0.93 | 0.78–1.10 | 0.408 |
| Irregular | 1.36 | 1.20–1.55 | <0.001 | 1.03 | 0.87–1.22 | 0.752 |
Univariate and multivariate Cox regressions to associate the extent of individual features per subject (range: 0–8) with CVD events.